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Genmab Stock: Breakthrough Therapy Sparks 5% Surge

Felix Baarz by Felix Baarz
August 7, 2025
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Danish biotech firm Genmab saw its shares jump over 5% to $22.70 after announcing groundbreaking Phase 3 trial results for its lymphoma therapy. The EPCORE FL-1 study showed a 79% reduction in disease progression or death risk for patients with relapsed follicular lymphoma when treated with Epcoritamab combined with Rituximab and Lenalidomide. Both primary endpoints were met, with a remarkable 95.7% response rate. The U.S. FDA has granted accelerated review, with approval expected by November 30, potentially making this the first bispecific antibody combo for second-line treatment of the disease in the U.S.

Financial Momentum and Pipeline Strength

Genmab’s revenue grew 19% to $1.64 billion in H1 2025, driven by blockbuster drugs DARZALEX and Kesimpta. Operating profit nearly doubled to $548 million, prompting raised full-year guidance. Beyond Epcoritamab, the company is advancing Rinatabart sesutecan for endometrial cancer, bolstering its oncology portfolio. A strategic partnership with a major pharma firm enhances global commercialization prospects, positioning Genmab as a key player in innovative cancer therapies.

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Felix Baarz

Felix Baarz

My name is Felix Baarz, and I look back on over fifteen years of experience as a business journalist. I have always been fascinated by the mechanisms and dynamics of global financial markets as well as the complex economic and political interconnections that shape our world. With this passion, I have made a name for myself as an expert on international financial markets and dedicate myself with great commitment to making even the most complex topics understandable and accessible to my readers. My roots lie in Cologne, where I was born and raised. Early on, my curiosity about economic topics and international developments sparked my interest in journalism. After completing my studies, I began my career as a business editor at a respected German trade publication. Here I laid the foundation for my professional career, but my curiosity soon drew me out into the wider world. A turning point in my life was moving to New York, where I lived for six years and gained insight into leading media houses. In this vibrant metropolis, I was able to report firsthand from the heart of the global financial world. From daily developments on Wall Street to major economic policy decisions that make waves worldwide, I had the opportunity to write about central topics that move people and markets alike. This time shaped my perspective and sharpened my view of global interconnections.

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