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Major Funds See Value in BioNTech’s Depressed Shares

Dieter Jaworski by Dieter Jaworski
December 13, 2025
in Analysis, Pharma & Biotech, Turnaround
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BioNTech Stock
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While BioNTech stock trades near its 52-week low, a significant shift is occurring behind the scenes. Prominent institutional investors are interpreting the current valuation as a compelling buying opportunity, with several asset managers making substantial additions to their holdings. This accumulation coincides with renewed optimism from equity researchers regarding the company’s long-term pipeline.

Analysts Revise Targets Upward on Pipeline Progress

The bullish sentiment is partly fueled by positive analyst commentary. Berenberg recently reaffirmed its buy rating on the stock and increased its price target to $155. This adjustment suggests a potential upside of over 60% from recent trading levels.

The primary driver for this upgraded outlook is progress in BioNTech’s oncology portfolio. Encouraging data for cancer drug candidates Gotistobart and Pumitamig—the latter developed in collaboration with Bristol Myers Squibb—are bolstering confidence in the firm’s post-pandemic strategy. Furthermore, a recent study published in npj Vaccines has provided scientific counter-evidence to previous concerns about DNA impurities in mRNA vaccines, removing a psychological overhang for the stock.

Institutional Accumulation Signals Confidence

Recent regulatory filings reveal a clear trend of accumulation by major financial institutions. The most striking move came from Bellevue Group AG, which boosted its stake in the Mainz-based biotech firm by a remarkable 340% during the reporting period.

Should investors sell immediately? Or is it worth buying BioNTech?

This was not an isolated event. Data from December 13th highlights broader institutional interest:
* Gilder Gagnon Howe & Co. increased its holding to a total value exceeding $71 million.
* Profund Advisors and Banco Bilbao Vizcaya Argentaria also expanded their respective positions.

These transactions indicate that professional investors view the share price of approximately €80 as an attractive entry point rather than a fundamental risk.

Strong Revenue Offsets Quarterly Earnings Miss

The fundamental picture presents a mixed view. For the third quarter, BioNTech reported a per-share loss, missing profit expectations. However, the company delivered a positive surprise on the top line: revenue of $1.78 billion significantly surpassed estimates and represented a 22% increase compared to the same period last year.

The current market scenario is defined by the gap between the stock’s depressed valuation and expert expectations. While the shares have declined roughly 28% over the past year, the average analyst price target stands close to $138. With confirmed backing from major investors, the focus now shifts to whether continued pipeline advancements can bridge this discrepancy in the coming months.

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Tags: BioNTech
Dieter Jaworski

Dieter Jaworski

About Dieter Jaworski From a numbers-obsessed child to creating his first investment newsletter. Even as a child, Dieter Jaworski's mother couldn't believe how fascinated he was with numbers. This early passion for mathematics and data analysis laid the foundation for a successful career in financial markets and investment analysis.
Areas of Expertise:
  • Quantitative Analysis
  • Financial Newsletter Publishing
  • Data-Driven Investment Strategies
  • Market Pattern Recognition
Dieter's unique approach combines his natural affinity for numbers with decades of market experience, providing investors with data-driven insights and practical investment strategies.

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