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Title Launch of KARDIA3 Trial Evaluating Zilebesiran for Uncontrolled Hypertension

Elaine Mendonca by Elaine Mendonca
March 5, 2024
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On March 5, 2024, Alnylam and Roche announced the launch of the KARDIA-3 Phase 2 trial. This study will assess the effectiveness of Zilebesiran as an additional treatment option for individuals with high cardiovascular risk and uncontrolled hypertension, despite being on two to four standard antihypertensive medications.

The goal of the KARDIA-3 study is to cater to the needs of adults struggling with uncontrolled hypertension at a high risk of cardiovascular complications. This trial builds upon the encouraging outcomes of previous research such as KARDIA-1 and KARDIA-2.

Roche’s partnership with Alnylam in the realm of cardiovascular research underscores their dedication to discovering groundbreaking therapies for conditions like high blood pressure.

Alnylam Pharmaceuticals, Inc. (ALNY) Stock Price Declines on March 5, 2024: Potential Rebound Ahead?

On March 5, 2024, Alnylam Pharmaceuticals, Inc. (ALNY) experienced a decline in its stock price, trading near the bottom of its 52-week range and below its 200-day simple moving average. The stock closed at $150.04, a decrease of $2.57 or 1.68% from the previous market close. Despite the decline, there was a slight uptick in pre-market trading, with the stock rising $0.96. This indicates potential positive momentum for ALNY, possibly leading to a rebound in the stock price. Investors and analysts will be closely monitoring ALNY’s performance in the coming days to see if the pre-market gains can be sustained and if the stock can break out of its current downward trend. It will be important to watch for any news or developments that could impact ALNY’s stock price, such as clinical trial results, regulatory approvals, or market trends in the biopharmaceutical industry. Overall, ALNY’s stock performance on March 5, 2024, demonstrates the volatility and uncertainty in the stock market. Investors should exercise caution and conduct thorough research before making any investment decisions related to ALNY or any other stock.

Alnylam Pharmaceuticals Reports Strong Revenue Growth but Widening Net Loss: Financial Performance Analysis for 2024

On March 5, 2024, Alnylam Pharmaceuticals (ALNY) reported its financial performance for the past year and the fourth quarter of the fiscal year. The biopharmaceutical company posted total revenue of $1.83 billion for the year, representing a significant increase of 76.23% compared to the previous year. However, the total revenue remained flat at $439.72 million for the fourth quarter.

Despite the strong revenue growth, Alnylam reported a net loss of $440.24 million for the year, which was an improvement of 61.08% compared to the previous year. However, the net loss widened to $137.87 million for the fourth quarter, a decrease of 193.31% compared to the previous quarter.

Earnings per share (EPS) for Alnylam stood at -$3.52 for the year, showing an increase of 62.08% compared to the previous year. However, the EPS decreased to -$1.10 for the fourth quarter, a decline of 195.29% compared to the previous quarter.

Overall, Alnylam Pharmaceuticals showed strong revenue growth over the past year, but the company continues to face challenges in turning a profit. Investors may be concerned about the widening net loss and decreasing EPS in the most recent quarter. It will be important for Alnylam to focus on cost management and revenue growth strategies to improve its financial performance in the future. Investors should keep a close eye on the company’s upcoming quarterly reports to gauge its progress towards profitability.

Tags: ALNY
Elaine Mendonca

Elaine Mendonca

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